马钱苷

分析标准品,HPLC≥98%

Loganin

CAS号：18524-94-2

分子式：C17H26O10

分子量：390.38

MDL：MFCD00075645

别名：马钱素; 马钱素; 番木鳖苷; 马钱苷; 马钱苷; 马钱苷,番木鳖苷; 查看更多中文别名 收起;Meliatin; LOGANINE; Cuchiloside; Loganin; loganic acid methyl ester; 7-HYDROXY-6-DESOXYVERBENALIN; Loganoside

产品介绍

熔点：222℃

沸点：608.8℃ at 760 mmHg

外观：淡黄色结晶

敏感性：易吸潮

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(72篇)

72. [IF=5.7] Tong Zhang et al."Characterization of camptothecin biosynthesis in endophytic fungus from Camptotheca acuminate."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2025 Jul;:110208

71. [IF=5.7] Xingfan Li et al."Comparative role of oxidative balance, alkaloid production, and metabolites in exposure to red-to-blue light in Catharanthus roseus."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2025 Oct;227:110170

70. [IF=3.3] Xue Chen et al."Role of IGF1/IGFR signaling pathway in neuroprotective effect of Shengmai Dihuang Decoction on CIH-induced cognitive impairment."Journal of Traditional and Complementary Medicine.2024 Nov;:

69. [IF=3] Zhang Min et al."Investigation on the interaction between Jingui Shenqi pill and DPPC liposome mimetic biofilms."JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY.2025 Jan;:1-10

68. [IF=4.8] Binjie Liu et al."Aqueous extract of Cornus officinalis alleviate NAFLD via protecting hepatocytes proliferation through regulation of the tricarboxylic acid cycle."JOURNAL OF ETHNOPHARMACOLOGY.2025 Feb;341:119330

67. [IF=7] Ruina Liu et al."MCnebula analysis combined with alpha-glucosidase inhibitory screening reveals potential chemical contributors to efficacy enhancement of natural products after processing."FOOD RESEARCH INTERNATIONAL.2025 Mar;205:115985

66. [IF=4] Qiming Zhao et al."Sustainable stable extraction of anti-osteoporotic compounds from Cornus officinalis by osteoblast membrane bionic multifunctional carbonaceous microspheres composite column."JOURNAL OF FOOD COMPOSITION AND ANALYSIS.2025 Jun;142:107493

65. [IF=3.8] Tang Zhiqiang et al."Expression analysis and functional study of honeysuckle MYB transcription factors under drought stress."Scientific Reports.2025 Apr;15(1):1-14

64. [IF=1.9] Yingjian Guo et al."Enrichment optimisation and identification of total iridoid glycosides from Lonicera japonica Thunb. and its anti-inflammatory activity."NATURAL PRODUCT RESEARCH.

63. [IF=3.1] Mengyu Qian et al."A comprehensive quality evaluation strategy for ReDuNing injection by integrating UPLC-Orbitrap MS/MS profile and biological potency combined with multivariate statistical analysis."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2024

62. [IF=3.4] Jiaming Ge et al."To elucidate the bioactive components of Lamiophlomis Herba in the treatment of liver fibrosis via plasma pharmacochemistry and network pharmacology."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS".2024 May;:116204

61. [IF=5.9] Ningning Zhang et al."Morphological, chemical and genetic analyses reveal high diversity and blurred genetic boundaries in Cornus officinalis Siebold & Zucc. in China."INDUSTRIAL CROPS AND PRODUCTS.2024 Mar;209:117941

60. [IF=5.5] Mingzhu Gong et al."Role of BDNF–TrkB signaling in the antidepressant-like actions of loganin, the main active compound of Corni Fructus."CNS Neuroscience & Therapeutics.2023 Jul;:

59. [IF=2.8] Xudong Huang et al."Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling."TOXICON.2023 Jun;:107202

58. [IF=5.6] Xiaolin Yang et al."Corni Fructus extracts ameliorate Streptozotocin-Induced diabetes in mice via regulating AMPK/ACC/CPT-1 signaling pathway."Journal of Functional Foods.2023 Aug;107:105661

57. [IF=4.755] Wang Ya-Nan et al."The interaction of Yougui pill and its disassembled prescriptions with liposome mimetic biomembrane."JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY.2023 Mar;:1-10

56. [IF=5.581] Yan Wang et al."Metabolomics Analysis of Different Tissues of Lonicera japonica Thunb. Based on Liquid Chromatography with Mass Spectrometry."Metabolites.2023 Feb;13(2):186

55. [IF=1.698] Mengjie Xue et al."Illumination on Chemical Compounds from Qufeng Zhitong Capsule and Its Potential Pharmacological Mechanism against Rheumatoid Arthritis Based on UHPLC/Q-Orbitrap-MS Combined with Network Pharmacology Analysis."International Journal of A

54. [IF=1.698] Jinyan Wu et al."Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS."International Journal of Analytical Chemistry.2022 Oct 15;2022:142380

53. [IF=2.594] Xue Mengjie et al."Quantitative Analysis of Multicomponents in Qufeng Zhitong Capsule and Application of Network Pharmacology to Explore the Anti-Inflammatory Activity of Focused Compounds."Journal of Analytical Methods in Chemistry.2022;2022:4229945

52. [IF=3.693] Li Cao et al."Cornus officinalis vinegar reduces body weight and attenuates hepatic steatosis in mouse model of nonalcoholic fatty liver disease."JOURNAL OF FOOD SCIENCE

51. [IF=3.935] Yi-Jie Qian et al."Quality evaluation of raw and processed Corni Fructus by UHPLC-QTOF-MS and HPLC coupled with color determination."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 Sep;218:114842

50. [IF=6.53] Pan Sun et al."Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis."BIOMEDICINE & PHARMACOTHERAPY. 2022 Jun;150:112975

49. [IF=3.373] Yu Yao et al."UPLC–MS/MS method for the determination of the herb composition of Tangshen formula and the in vivo pharmacokinetics of its metabolites in rat plasma."Phytochemical Analysis. 2021 Dec 14

48. [IF=3] Hui-Qin PAN et al."Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos."Chin J Nat Medicines. 2021 Jan;19:70

47. [IF=3.24] Zhichen Cai et al."Metabolomics characterizes the metabolic changes of Lonicerae Japonicae Flos under different salt stresses."Plos One. 2020 Dec;15(12):e0243111

46. [IF=3.373] Zhichen Cai et al."A comprehensive study of the aerial parts of Lonicera japonica Thunb. based on metabolite profiling coupled with PLS-DA."Phytochem Analysis. 2020 Nov;31(6):786-800

45. [IF=3.935] Hengqiang Zhao et al."An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicerae Japonicae."J Pharmaceut Biomed. 2019 Oct;175:112758

44. [IF=4.451] Xiao Han et al."An iridoid glycoside from Cornus officinalis balances intestinal microbiome disorder and alleviates alcohol-induced liver injury."J Funct Foods. 2021 Jul;82:104488

43. [IF=4.545] TingTing Zhao et al."Tangshen formula modulates gut Microbiota and reduces gut-derived toxins in diabetic nephropathy rats."Biomed Pharmacother. 2020 Sep;129:110325

42. [IF=5.396] Binkai Han et al."Ultrasound-assisted enzymatic extraction of Corni Fructus alpha-glucosidase inhibitors improves insulin resistance in HepG2 cells."Food Funct. 2021 Oct;12(20):9808-9819

41. [IF=3.647] Kai Liu et al."Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products."Life Sci. 2015 Feb;123:78

40. [IF=4.142] Ji  Wenhua et al."Superhydrophilic molecularly imprinted polymers based on a single cross-linking monomer for the recognition of iridoid glycosides in Di-huang pills."Anal Bioanal Chem. 2018 Oct;410(25):6539-6548

39. [IF=4.759] Wenhua Ji et al."Water-compatible micron-sized monodisperse molecularly imprinted beads for selective extraction of five iridoid glycosides from Cornus officinalis fructus."J Chromatogr A. 2017 Jun;1504:1

38.  Cai, Z, Liao, H, Wang, C, et al. A comprehensive study of the aerial parts of Lonicera japonica Thunb. based on metabolite profiling coupled with PLS-DA. Phytochemical Analysis. 2020; 31: 786– 800. https:##doi.org/10.1002/pca.2943

37.  Tao, Yi, et al. "Integrating UHPLC–MS/MS quantification and DAS analysis to investigate the effects of wine-processing on the tissue distributions of bioactive constituents of herbs in rats: Exemplarily shown for Dipsacus asper." Journal of Chromatography

36.  Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,

An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera

35.  Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,

An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera

34.  Xiao Han, Jia Liu, Yingfeng Bai, Aiwu Hang, Tulin Lu, Chunqin Mao,

An iridoid glycoside from Cornus officinalis balances intestinal microbiome disorder and alleviates alcohol-induced liver injury,

Journal of Functional Foods,

Volume 82,

2021,

104488,

ISSN

33.  Liu, Kai, et al. "Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products." Life sciences 123 (2015): 78-85.https:##doi.org/10.1016/j.lfs.2

32.  Liu, Kai, et al. "Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products." Life sciences 123 (2015): 78-85.https:##doi.org/10.1016/j.lfs.2

31.  蔡芷辰,陈欢,杨蓉,陈佳佳,王程成,谈梦霞,陈佳丽,梅余琪,魏丽芳,殷圣鑫,刘训红.基于液相色谱-串联质谱结合多元统计分析盐胁迫下金银花代谢产物积累的变化[J].南京中医药大学学报,2020,36(05):584-592.

30.  凌霄,张辉,李伟霞,牛璐,唐进法,任献青.祛风消癜合剂UHPLC指纹图谱的建立[J].中成药,2020,42(11):2857-2862.

29.  王玲娜, 孙希芳, 张芳,等. 不同发育时期金银花颜色与活性成分的相关性分析[J]. 中草药, 2017, 15(v.48;No.602):171-177.

28.  朱姮, 于金倩, 刘倩,等. 基于RRLC-DAD-ESI-Q-TOF-MS技术的山东金银花多指标定量指纹图谱分析[J]. 中国实验方剂学杂志, 2017, 023(019):82-89.

27.  马云, 王尧尧, 王蕾,等. 忍冬花发育期间形态与13种活性成分含量变化[J]. 中药材, 2018, 041(007):1559-1565.

26.  王玲娜,张芳,李佳,刘红燕,姜秋,张永清.金银花新品种“华金6号"药材品质比较研究[J].中药材,2019,42(09):2030-2035.

25.  焦红军, 董风其, 陶明晖,等. 祛风消癜合剂质量标准研究[J]. 中国药业 2020年29卷13期, 56-59页, ISTIC CA, 2020.

24.  白一丹  乔洲  薛敬伟 等. 参松养心胶囊多组分同时测定及方法学验证[J]. 药物分析杂志  2018  v.38(08):80-90.

23.  杨健, 蒋超, 金艳,等. 密银花对照药材标定标准的研究[J]. 中国中药杂志, 2017(19).

22.  于晓  李松涛  刘建升 等. RP-HPLC法同时测定忍冬藤中绿原酸 马钱苷 当药苷含量的研究[J]. 山东农业科学  2015  47(9):124-124.

21.  韩根利  刘宏胜  王树森 等. RP-HPLC法同时测定山茱萸萜类制剂中莫诺苷 马钱苷 山茱萸新苷 齐墩果酸及熊果酸[J]. 中草药  2017  48(024):5168-5173.

20.  白昱旸, 陈强, 梁丽娜,等. 祛风及开窍类引经药对六味地黄丸有效成分眼内分布的影响[J]. 中国中医眼科杂志, 2017.

19.  吴云皓. 马钱苷对糖基化终末产物诱导足细胞损伤的保护作用[J]. 中国药理学通报, 32(03):332-336.

18.  戴国英, 吕兴, 许惠琴,等. 马钱苷对糖基化终末产物致肾系膜细胞内质网应激的保护作用机制[J]. 中草药, 2016(21).

17.  刘凯, 许惠琴, 吴佳蕾,等. 马钱苷、莫诺苷对AGEs损伤HUVEC的增殖的影响[J]. 中药药理与临床, 2014, 030(003):53-57.

16.  李晓芳, 刘云宏, 马丽婷,等. 远红外辐射温度对金银花干燥特性及品质的影响[J]. 食品科学, 2017(15):81-88.

15.  李富欣, 于蓓蓓, 刘瑾,等. 茯黄颗粒的质量标准研究[J]. 西部中医药, 2019, 032(002):P.44-48.

14.  于颖超, 倪健, 高利利,等. 芪箭颗粒的高效液相色谱指纹图谱研究. 中南药学, 2020年18卷2期, 231-234页, ISTIC CA.

13.  陶玉菡,许惠琴,李莉,农伟虎,李伟.生地、山茱萸抑制和清除糖基化产物的效应成分研究[J].中药药理与临床,2013,29(04):30-33.

12.  雷小小, 苏艳莹, 桂卉. 正交试验优选山茱萸总环烯醚萜苷的提取、纯化工艺[J]. 中南药学, 2018.

11.  苏艳莹, 雷小小, 桂卉,等. 星点设计-效应面法优化山茱萸总环烯醚萜苷脂质体的制备工艺[J]. 中国药房, 2018, 29(19):25-29.

10.  罗峰. 星点设计-效应面法优化山茱萸-白芍提取工艺研究[J]. 中医学报, 2019(7).

9.  刘芳, 武勇. 山茱萸果实生物量积累及莫诺苷,马钱苷含量的动态变化研究[J]. 长治医学院学报, 2020(3):169-172.

8.  郑梅, 刘富垒, 薛敬伟,等. 基于肝微粒体和指纹图谱研究六味地黄丸与硝苯地平的药物相互作用[J]. 中国药科大学学报, 2018, 49(02):70-76.

7.  马彦江, 陈天朝, 鲁静,等. 均匀设计法优选山茱萸九蒸九晒炮制工艺[J]. 中医药信息, 2020, 037(003):17-21.

6.  曾杰. 右归饮HPLC指纹图谱研究及9种成分定量分析[J]. 中草药  2017  48(24):5143-5150.

5.  朱俊平  魏佳明  刘瑞连 等. 养精种玉汤的"点-线-面"质量标准分析[J]. 中国实验方剂学杂志  2019(21):12-18.

4.  蔡黎明 周盈 蔡宝昌 刘芳 皮文霞.不同大孔树脂富集山茱萸中环烯醚萜苷的效果比较[J].中国实验方剂学杂志 2013 19(13):39-41.

3.  李伟  许惠琴  陶玉菡 等. RP-HPLC法测定山茱萸环烯醚萜总苷中马钱苷和莫诺苷含量[J]. 南京中医药大学学报  2014  30(001):90-92.

2.  张琳  汪轩  邢婧 等. HPLC-DAD同时测定左归丸药液中没食子酸 原儿茶酸 绿原酸 马钱苷 阿魏酸含量[J]. 药物分析杂志  2016  036(008):1364-1369.

1.  丁艳霞 王晓琴 杨倩.HPLC-DAD双波长法同时测定小秦艽花中5个成分的含量[J].药物分析杂志 2020 40(02):227-231.

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