麦冬皂苷D

分析标准品,HPLC≥98%

Ophiopogonin D

CAS号：41753-55-3

分子式：C44H70O16

分子量：855.02

产品介绍

熔点：263-265℃

比旋光度：(c, 0.66 in Py)-107.9

外观：白色粉末

溶解性：可溶于甲醇、乙醇、DMSO等有机溶剂

敏感性：易吸潮

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(18篇)

18. [IF=4.4] Haoxiang Sun et al."Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway."Frontiers in Pharmacology.2025 Apr;16:

17. [IF=7.9] Xiao Shen et al."Ophiopogonin D alleviates acute lung injury by regulating inflammation via the STAT3/A20/ASK1 axis."PHYTOMEDICINE".2024 Mar;:155482

16. [IF=1.1] Ji-Yong FU et al."Simultaneous determination of 19 constituents in the Jian-Nao-Ning mixture using high-performance liquid chromatography-tandem mass spectrometry."Separation Science Plus".2024 Feb;:2300222

15. [IF=5.195] Chao Meng et al."Complex components of Shengmai formula interact with organic cation transporter 2 (OCT2) in MDCK cells."JOURNAL OF ETHNOPHARMACOLOGY.2023 May;308:116278

14. [IF=3.614] Jing Liu et al."Phytochemical identification of Xiaoer Huanglong Granule and pharmacokinetic study in the rat using its seven major bioactive components."JOURNAL OF SEPARATION SCIENCE

13. [IF=4.207] Ziyu Cheng et al."Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis."J Cancer. 2022; 13(2): 715–727

12. [IF=2.289] Zhou  Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150

11. [IF=5.34] You-Ping Wu et al."Evidences for the mechanism of Shenmai injection antagonizing doxorubicin-induced cardiotoxicity."Phytomedicine. 2021 Jul;88:153597

10. [IF=5.34] Tao Zhan et al."The major effective components in Shengmai Formula interact with sodium taurocholate co-transporting polypeptide."Phytomedicine. 2019 Jun;59:152916

9. [IF=0] Xiaoyan Huang et al."Ophiopogonin D Reduces Myocardial Ischemia-Reperfusion Injury via Upregulating CYP2J3/EETs in Rats."Cell Physiol Biochem. 2018;49(4):1646-1658

8.  Huang X, Wang Y, Wang Y, Yang L, Wang J, Gao Y: Ophiopogonin D Reduces Myocardial Ischemia-Reperfusion Injury via Upregulating CYP2J3/EETs in Rats. Cell Physiol Biochem 2018;49:1646-1658. doi: 10.1159/000493500

7.  Wu, Lingna, et al. "Interactions of the major effective components in Shengmai formula with breast cancer resistance protein at the cellular and vesicular levels." Biomedicine & Pharmacotherapy 133 (2021): 110939.https:##doi.org/10.1016/j.biopha.2020.11093

6.  余健, 徐晓珍, 顾利强,等. 高效液相色谱-串联质谱法同时测定参麦注射液中9种皂苷[J]. 中华中医药学刊, 2014.

5.  孟晨, 袁彩华, 张晨晨,等. 麦冬皂苷D通过减轻内质网应激对阿霉素所致心肌损伤产生保护作用[J]. 药学学报, 2014(8):1117-1123.

4.  金虹, 王化东, 何礼,等. 川产麦冬及其须根组织学与麦冬皂苷量的对比研究[J]. 中草药, 2014, 45(7):1002-1005.

3.  徐小芳, 陈文婷, 刘敏,等. 复方附子口服液质量标准的研究[J]. 中成药, 2016, 38(004):815-819.

2.  何礼  金虹  梁雪兰 等. HPLC测定川麦冬块根及须根中的麦冬皂苷D[J]. 华西药学杂志  2014(5):583-584.

1.  缪菊连  黄照昌  王成军 等. HPLC-ELSD法测定生脉饮中麦冬皂苷D[J]. 中成药  2015  37(002):462-464.

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